E5: Application to bilogy and medicine
The beam line for biological irradiation eonsists of a
device for making a homogeneous irradiation field and a beam
monitoring system: a wobbler magnet coupled with a gold-foil
scatterer, a PPAC, and an ionization chamber. An irradiation
apparatus is inst end of this beam line. The beam
homogeneity in the irradiation field of 50 x 50 mm2 is
measured to be better than 10% using a two dimensional PPAC.
The Figure shows a schematic diagram of the beam line. A
side view of the biological irradia apparatus is shown in
the figure, together with its photograph. Currently, the
following subjects are under way.
(1) Neoplastic cell transfbrmation by heavy ions.
The goal of this study is to elucidate the mechanisms of
biological effects of heavy ions and to offer the date baset
for the radiation risk estimation.
(2) Effbct of heavy ions on fish embryonic development.
To assess the radiation damage during space travel, a small
teleost fish, Medaka, is an excellent experimental species
because of its relatively short life eycle(matu-ration
within 3-6 months), high reproductive capacity and ease of
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